Or No Decline in Bone Mass

Continuous fat-free mass decline in COPD: fact or fiction?

Patients with chronic obstructive pulmonary disease (COPD) generally have lower fat-free mass (a surrogate marker of skeletal muscle mass) compared with their healthy peers [1, 2], and this is associated with decreased functional capacity [3], the presence of other comorbidities (e.g. osteoporosis and renal impairment) [4] and increased mortality risk [5]. To date, longitudinal observational st...

Fertility decline; no mystery

The economic opportunity hypothesis states that perceived shrinkage of opportunity discourages women or couples from embarking on marriage or reproduction. On the contrary, the sense that opportunity is expanding encourages couples to raise their family-size target. The hypothesis assumes that humans are genetically programmed to maximize successful reproduction by having more offspring when en...

Genetically Modified Food: Yes or No?

No increased bone formation around alendronate or omeprazole loaded bioactive bone cements in a femoral defect.

Alendronate and omeprazole have been found to influence bone healing by interfering with osteoclastic activity, resulting in increased bone formation. The biological effect of these conventional drugs, incorporated into bioactive bone cement (G2B1), was investigated in a rabbit model. The 2 materials and a control were inserted in defects created in the femoral condyle of rabbits. Implantation ...

Bone mass, lean mass, and fat mass: same genes or same environments?

The contributions of genetic and environmental factors to the association among bone mineral density (BMD), lean mass, and fat mass were assessed in the Sydney Twin Study of Osteoporosis (Australia), 1995-1996, in 57 monozygotic and 55 dizygotic female twin pairs of Caucasian background, aged 52.8 (standard deviation, 13) years. In multiple regression analysis, lean mass was a significant deter...